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Clinical efficacy and mechanism of action of Chinese herbs and active ingredients for DKD treatment.
Polyphenols Breviscapine, supplied by Bioactive Ingredients, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Clinical efficacy and mechanism of action of Chinese herbs and active ingredients for DKD treatment.

Journal: Renal Failure

Article Title: Advances in oxidative stress in pathogenesis of diabetic kidney disease and efficacy of TCM intervention

doi: 10.1080/0886022X.2022.2146512

Figure Lengend Snippet: Clinical efficacy and mechanism of action of Chinese herbs and active ingredients for DKD treatment.

Article Snippet: It has been proven that Chinese herbal medicines and their bioactive ingredients, such as polyphenols (e.g., breviscapine, puerarin, resveratrol, safflower yellow, silymarin, curcumin, icariin, and tanshinone), polysaccharides (e.g., lycium barbarum polysaccharides, astragalus polysaccharides, ramulus mori polysaccharides, and Chinese Yam polysaccharides), alkaloids (e.g., berberine, tripterygium glycosides, ligustrazine, and emodin), and saponins (e.g., astragaloside and ginsenoside), can improve glucose metabolism and reduce renal pathological changes via multiple anti-inflammatory and anti-fibrotic pathways involved in oxidative stress, playing a nephroprotective role.

Techniques: Activity Assay, Activation Assay, Expressing, Protein-Protein interactions